Andriana Avent led the Tigers with 14 points, three rebounds, an assist, a block and a steal.
Avent was one of just three to record double-figure points as the shooting touch could not be found all throughout the contest with tsu shooting just 27.5 percent (19-for-69) from the field and 21.4 percent from long range (6-for-28).
The Mavericks started the season-opening contest for both schools with an 8-0 run before TSU got the board with 7:24 left in the opening quarter on a putback by Skye Green.
Texas Southern would get as close as 10-6 on a pair of made free throws from Donterria Brown with 6:11 to go in the first quarter before UTA would close out the stanza with a 21-9 run including a stretch of 3:12 later in the quarter that saw TSU go scoreless before Micah Gray's driving layup ended the drought.
Taniya Lawson's layup with 5:34 left in the second quarter then Jaida Belton's fast-break layup just 19 seconds later would pull the Tigers to within 18 at 44-26, but that would be the closest TSU would get the rest of the way as UTA slowly increased its lead throughout the rest of the game.
Brown added 12 points and tied for a game-high seven rebounds with Green, who finished with four points.
Lawson was the third member of the Tigers squad that finished in double-figures with 11 points to go along with five rebounds and two assists.
TSU battled on the boards all night despite being down by as many as the Tigers were throughout the second half as the Tigers equaled the Mavericks with 46 rebounds,
UTA's Kayla White led all scorers with 17 points as teammate Jireh Washington hauled in a 12-point, 11-assist double-double.